I’m not diabetic and the situation with insulin fills me with a white hot rage.
Canadians: invented drug and patent it freely
Americans: Finds way to kill the most people possible while making the most amount of money
To be fair, the killing isn’t the point; they’re the product. Its just that profit is God, so killing in its name is justified.
Killing poors for the joy of it? That’s just an evil bonus.
Meanwhile, 10 euros per vial here in Europe. At least his original plan for widespread and easy availability has partially succeeded.
In civilized countries at least.
In brazil 36 reais (about 6 euro). The US is a joke. (And im 99% sure you can also get it for free if you use the public health network)
I have mental health disabilities in the USA and my meds are at zero cost because I literally have had absolute zero income for the past 5 years.
You wouldn’t believe how much those mood stabilizer/antidepressant cocktails stack up proportionally when I was able to scrape by on $15 an hour.
The system set me up to fail with how shitty it is, if healthcare wasn’t crap I could be contributing to society without crippling myself.
If you talk about killing the few people like these that are the root cause of all these problems, you’re a terrorist. You go to jail
These people actually kill people by the thousands, millions, and we call them smart CEO’s and celebrate them 🥂
Free Luigi.
There is plenty of propaganda on social media to exalt the billionaires and CEOs. Instagram is especially really bad at it. I don’t know why the algorithm suggest heavily to me about “entrepreneur” pages (maybe my investing platform sold my data), although some of these pages whitewash literal fraudulent and underhanded behaviours from celebrity CEOs and fraudsters, spinning their past behaviours as “another way to get rich”. I also think the posts and profiles were written by bots, because the language and syntax used sound almost identical from one another, in spite of these profiles supposedly being independent from one another.
Remember Remember the 4th of December
Making an AI meme of Luigi as a Saint is one thing.
Making a painting and having it casually displayed in your room is a whole other level.
Also, I can’t believe it’s already been a year.
Yea I guess but my mom was destroyed by our cruel and heartless system. She’s gone now but painting this helped me reconnect with the glimmer of hope we all felt for a moment after this happened. It also helped process the trauma I myself went through as her caregiver not being able to access what she needed
Please support the Open Insulin Foundation who are creating an open source model for insulin production! Such an important project!
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If he wanted it to be freely available, why did he even sell the patent ? Just disclaim at the patent office. Selling is just asking the new holder to start enforcing.
They sold the patent to the University of Toronto, so they didn’t exactly sell it to a for-profit patent troll.
But also, that was in 1923, so the patent has long since expired.
I mean, that’s better than selling to a private person, still feels weird, since disclaiming a patent is absolutely possible, and has a 100% chance of leading to the desired outcome, vs whatever small chance there may be that the University starts taking profits on it. Or even just sees themselves forced to sell the patent, because of potential financial issues.
Yeah, the risk is small, but eliminating it in it’s entirety would’ve been easily possible, so it just feels a bit weird he didn’t do it.
Remember, the 1920s is long ago. Giving the patent to the equivalent of a non-profit organisation was probably better than disclaiming it, since it’s easier to have one large, well-known entity that will fight off people trying to re-patent it than to disclaim it and hope that no patent clerk ever lets a fraudulent re-patent go through.
In 1920 you couldn’t just google for prior art when fighting a fraudulent patent.
Ok, that is a fair point I hadn’t previosuly considered. Though disclaiming a patent doesn’t loose you all legal recourse.
If someone else tries to repatent it, even if it gets approved, you can still file a challenge against the new patent with the PTO. You (or anyone else, really) would also have a virtually guaranteed court win, even if someone got the patent through and tried to enforce it. All you’d have to prove in court is that prior art of the invention exists, therefore the patent is invalid and unenforceable, granted or not, so it’s unlikely someone would even bother trying to enforce such a patent. A previous, diclaimed patent, of literally the identical technology being on record is pretty iron clad and unavoidable evidence that the patent isn’t original.
Nowadays you just google for other patents and done. But back then, I guess that searching for prior art was quite a lot more difficult. Gifting the patent to an university so that they defend open access to the patent sounds like a more reliable plan.
I mean, even nowadays patents are greenlit my patent offices even though there’s clear prior art (Nintendo’s recent patent for catching monsters in a ball in a game comes to mind, which Nintendo would have to have patented before publishing their first game with that mechanic around 30 years ago), and even today it’s really difficult and expensive to get such a clear nonsense patent invalidated.
So difficult that e.g. Palworld opted to change the mechanic instead of fighting the patent.
So I do understand why someone would instead gift the patent to an university under the condition that they keep access to it open, especially 100 years ago.
That logic applies identically to a valid patent. For the issues you mention, there is no distinction between the patent being filed at the PTO and still valid, or being filled at the PTO and disclaimed. In terms of the enforcibility, and patentability of a ““new”” inventions with prior art, there is no legal distinction whatsoever between the prior art being a disclaimed or a valid patent, so I don’t think that’s a valid reason to not disclaim it.
Anyone who wants to repatent the process and harass people using it, would have an equally hard/easy time doing so, if the patent is disclaimed or valid.
The only real legal distinction between a disclaimed and valid patent is that the orignal patent holder can’t enforce the disclaimed one. And since that was the intended goal here, disclaimment feels like the obvious best choice.
That logic applies identically to a valid patent.
The difference is that in the case of transferring the patent to the university, there’s a legal department at the ready to defend the patent. The same is not the case for a disclaimed patent.
Capitalism is economic terrorism.
California is contracting its own insulin supply and it’ll be available for $11 a pen starting Jan 1, 2026. I know not every state can or are willing to do this but just throwing out some examples and hopefully optimism to somehow fight the American decline from within it. We’re in a unique position as our state economy is larger than most countries but I am hopeful we will throw our weight around to counter the bs. https://www.chhs.ca.gov/blog/2025/10/17/governor-newsom-announces-affordable-calrx-insulin-11-a-pen-will-soon-be-available-for-purchase/
contracting is an interesting choice of word since it could mean decreasing
That’s called a homophone.
Is there any reason a diabetic has to get the newer patented formulas instead of the old one that the pic talks about which is regularly sold for around $25 a vial in the US without insurance?
I know the new stuff works faster and you don’t have to worry about your diet as much so I’m sure it’s much easier, but why would you have to die instead of just managing your diet and using the $25 stuff for a month in this emergency situation?
Don’t get me wrong all medicine should be free and stuff but like, why die instead of switching to the cheap stuff and dietary management for a month?
Insulin is not permanently shelf stable, and will still expire in the fridge.
Diabetics usually start with a long-acting insulin to keep blood sugar from naturally rising plus a fast-acting insulin for corrections and to compensate for food.
The old style of just giving 2 long-acting shots of mixed insulin is mostly obsolete, except for legacy patients, some pregnant patients, and other special cases I can only theorize.
A good number of diabetics only use fast acting insulin in a pump, receiving microdoses every minute.
To switch brands of insulin, much less therapies in any circumstance requires a doctor’s visit.
With all that said, the insurance company will often replace a medication in the event of an accident, typically only once a year.
Without that, a patient might be able to find a charity they will assist them.
You also may be able to travel to the next state over where the cost of insulin is regulated.
Failing all other options, it is better to check yourself in to the hospital as your sugar begins to rise and tell them that you cannot control your blood sugar.
I don’t think I ever had insurance in the US where checking into the hospital for any amount of time would cost less than $800 out of pocket.
Unless I had already reached my annual deductible, that is.
Unless I had already reached my annual deductible, that is.
“Hey good news! After about 35% of your annual income is spent on medical bills on top of your triple digit monthly premiums… That health insurance starts to kick in!”
(Until it resets at the end of the year. Teehee!)
The deductible system is ridiculous.
It truly is amazing how an entire industry makes billions by literally avoiding delivering the most basic service it’s paid for at every possible turn.
The extra ridiculous thing is how they deny services that a doctor says are medically necessary… and not even in a reasonable way, in an abusive way. Like the system that automatically denies 60,000 things an hour or whatever, and count on people wasting tons of time to challenge it. Or when they have an ophthalmologist review your kidney disease and say that some treatment isn’t warranted. And that’s even after you’ve paid your stupid deductible costs for the year.
Naive question from a european: Aren’t there companies on the market who can offer a cheaper price and therefore beat greedy competitors?
the problem is that there is natural (as in, unmodified) cheap generic insulin available, it’s just that it sucks compared to everything else. you see, insulin is a peptide that is supposed to appear, do some signalling, then disappear and unmodified insulin copies this thing exactly. the problem is, most of the time when peptide is supposed to work as a pharmaceutical, you don’t want to do that, you’d like insulin to last longer than usual, which means changes to it that make breakdown slower, or adding something that makes it stick to albumin, which has similar effect because it hides insulin somewhere enzymes can’t reach it and also it makes it start acting slower. this means less frequent dosing and less changes in insulin activity over time. there are also other insulins that start acting faster than natural, and this is also due to a couple of modifications in its structure
for another example, ozempic was not the first drug in its class, it’s also a modified peptide, and it can be injected s.c. once a week, compared to previous iteration (liraglutide) that requires daily injections. if natural peptide is injected i.m. instead, its halflife is half an hour, and in serum it’s only two minutes (it gets released a bit slower than it is metabolized)
manufacturing costs are about the same for any variant, most of it is in purification. patents for a couple of these have expired anyway by now, but if manufacturing is limited then price can be set arbitrarily high (see daraprim)
Oh wow, an actual nuanced response and genuine answer!
Also today I learned!
Responses don’t need to be nuanced to be useful.
Yeah, alright buttnugget.
Alright Caroline
???
Since your comment was entirely superfluous, I just replied in that same spirit.
US Healthcare = pay or die
Oh, it’s not that good.
It’s “Pay until you run out of money and can no longer take on more debt. Then die.”
yeah. insulin isn’t that expensive for me.
800$? Not even close.
Holy exaggeration.
We should be thankful for those of us not born in a third world country like the USA. 😌🙏
as an American I’m offended. how dare you compare third world countries to the US.
they may be small and unsuccessful but damn it they’re trying.
No no this is a “there are starving kids in America” thing; for a good chunk of the third world this shit would be literally unthinkable.
