I think even orally taking bioactive estrogen is not ideal because the body tries to filter it out. So when taking estrogen orally you need a much higher dosage then via injections or gels. With plant hormones you’d need an even higher dosage than that…
Usually? No. They’re usually taken orally, which is a problem because of low bioavailability and liver flooding. I’ve never seen a doctor even consider prescribing estradiol pills sublingually; I believe that is fairly exclusive to the DIY community, and even then it’s incredibly annoying having to take them 3-4 times per day to keep semi-consistent levels due to the 2 hour half-life (I speak from experience here, as I took estradiol sublingually before switching to injections). Sublingual administration is not a commonly recognized route of administration to medical providers, especially those who are not keeping up to date on the latest research, despite its benefits over oral; at least that is the case in the US.
That’s great! But most endocrinologists, and especially general practitioners are not aware of recent research in trans healthcare. I was simply correcting the idea that sublingual is more common than oral (this is especially true for cisgender women on HRT).
I think even orally taking bioactive estrogen is not ideal because the body tries to filter it out. So when taking estrogen orally you need a much higher dosage then via injections or gels. With plant hormones you’d need an even higher dosage than that…
E pills are usually taken sublingually. Much better to absorb the hormones inside the mouth instead of in the stomach.
Usually? No. They’re usually taken orally, which is a problem because of low bioavailability and liver flooding. I’ve never seen a doctor even consider prescribing estradiol pills sublingually; I believe that is fairly exclusive to the DIY community, and even then it’s incredibly annoying having to take them 3-4 times per day to keep semi-consistent levels due to the 2 hour half-life (I speak from experience here, as I took estradiol sublingually before switching to injections). Sublingual administration is not a commonly recognized route of administration to medical providers, especially those who are not keeping up to date on the latest research, despite its benefits over oral; at least that is the case in the US.
Hi, my doctor prescribed my pills sublingually. I did pick my doctor very carefully to work with one who is aware of current research.
That’s great! But most endocrinologists, and especially general practitioners are not aware of recent research in trans healthcare. I was simply correcting the idea that sublingual is more common than oral (this is especially true for cisgender women on HRT).