Asking for a friend.

  • homura1650@lemmy.world
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    4 days ago

    The Y chromosome does a bit more than just carry the SRY gene.

    There is a condition where a father’s SRY gene gets transfered to the X chromosome of a sperm, resulting in a child who is XX and SRY positive. [0]

    In all known cases, such men are infertile. Fertility treatment is the main source of diagnoses for this, as that is typically the only symptom.

    [0] This is de la Chapelle syndrome, although that syndrome also covers an even rarer situation of an XX SRY-negative child developing as a male.


    There is also Swyer syndrome where an XY individual develops as a female (typically due to a defact in SRY). Such individuals general do not go through natural puberty and require hormone therapy.